产品名称
Nkx-6.1 Rabbit Polyclonal Antibody
别名
NKX6-1; NKX6A; Homeobox protein Nkx-6.1; Homeobox protein NK-6 homolog A
蛋白名称
Homeobox protein Nkx-6.1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4825
Human Swissprot No.
P78426
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P78426/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18096
Mouse Swissprot No.
Q99MA9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99MA9
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=65193
Rat Swissprot Link
http://www.uniprot.org/uniprot/O35762
免疫原
Synthesized peptide derived from Nkx-6.1 . at AA range: 180-260
特异性
Nkx-6.1 Polyclonal Antibody detects endogenous levels of Nkx-6.1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008],
组织表达
Pancreatic beta cells.
信号通路
Maturity onset diabetes of the young;
功能
function:May be important for control of islet development and/or regulation of insulin biosynthesis.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Pancreatic beta cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
