BD-PT3141

Nkx-2.8 Rabbit Polyclonal Antibody

常规抗体

NKX2-8

Homeobox protein Nkx-2.8

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

26257

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26257

Q8IUT7

http://www.uniprot.org/uniprotkb/Q8IUT7/entry

The antiserum was produced against synthesized peptide derived from human NKX28. AA range:20-69

Nkx-2.8 Polyclonal Antibody detects endogenous levels of Nkx-2.8 protein.

WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

26kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015],

Brain,Tongue,

nucleus,

similarity:Belongs to the NK-2 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.