产品名称
NK-TR Rabbit Polyclonal Antibody
别名
NKTR; NK-tumor recognition protein; NK-TR protein; Natural-killer cells cyclophilin-related protein
蛋白名称
NK-tumor recognition protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4820
Human Swissprot No.
P30414
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P30414/entry
Mouse Swissprot No.
P30415
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P30415
免疫原
The antiserum was produced against synthesized peptide derived from human NKTR. AA range:784-833
特异性
NK-TR Polyclonal Antibody detects endogenous levels of NK-TR protein.
稀释度
WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008],
组织表达
Aorta endothelial cell,Blood,Epithelium,Fetal kidney,Human endometr
功能
catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,function:Component of a putative tumor-recognition complex. Involved in the function of NK cells.,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcellular location:Attached to the membrane via its N-terminus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
