产品名称
NK-3R Rabbit Polyclonal Antibody
别名
TACR3; NK3R; TAC3R; Neuromedin-K receptor; NKR; NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3
蛋白名称
Neuromedin-K receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6870
Human Swissprot No.
P29371
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P29371/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21338
Mouse Swissprot No.
P47937
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P47937
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24808
Rat Swissprot Link
http://www.uniprot.org/uniprot/P16177
免疫原
The antiserum was produced against synthesized peptide derived from human NK3R. AA range:401-450
特异性
NK-3R Polyclonal Antibody detects endogenous levels of NK-3R protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008],
组织表达
Brain,G-protein coupled receptors,PCR rescued clones,Placenta,
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Calcium;Neuroactive ligand-receptor interaction;
功能
function:This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,miscellaneous:The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.,PTM:The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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