产品名称
NK-2R Rabbit Polyclonal Antibody
别名
TACR2; NK2R; NKNAR; TAC2R; Substance-K receptor; SKR; NK-2 receptor; NK-2R; Neurokinin A receptor; Tachykinin receptor 2
蛋白名称
Substance-K receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6865
Human Swissprot No.
P21452
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P21452/entry
Mouse Swissprot No.
P30549
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P30549
免疫原
The antiserum was produced against synthesized peptide derived from human NK2R. AA range:301-350
特异性
NK-2R Polyclonal Antibody detects endogenous levels of NK-2R protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008],
组织表达
Bone marrow,Lung,Stomach,Trachea,
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Calcium;Neuroactive ligand-receptor interaction;
功能
function:This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,miscellaneous:The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
