产品名称
Nidogen Rabbit Polyclonal Antibody
别名
NID1; NID; Nidogen-1; NID-1; Entactin
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4811
Human Swissprot No.
P14543
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P14543/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18073
Mouse Swissprot No.
P10493
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P10493
Rat Swissprot Link
http://www.uniprot.org/uniprot/P08460
免疫原
The antiserum was produced against synthesized peptide derived from human NID1. AA range:219-268
特异性
Nidogen Polyclonal Antibody detects endogenous levels of Nidogen protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
nidogen 1(NID1) Homo sapiens This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix. [provided by RefSeq, Jul 2008],
组织表达
Brain,Placenta,Testis,
细胞定位
Secreted, extracellular space, extracellular matrix, basement membrane.
功能
function:Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions.,PTM:N- and O-glycosylated.,similarity:Contains 1 NIDO domain.,similarity:Contains 1 nidogen G2 beta-barrel domain.,similarity:Contains 1 thyroglobulin type-1 domain.,similarity:Contains 4 LDL-receptor class B repeats.,similarity:Contains 6 EGF-like domains.,subunit:Interacts with FBLN1 and LGALS3BP.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
