产品名称
NF-YC Rabbit Polyclonal Antibody
别名
NFYC; Nuclear transcription factor Y subunit gamma; CAAT box DNA-binding protein subunit C; Nuclear transcription factor Y subunit C; NF-YC; Transactivator HSM-1/2
蛋白名称
Nuclear transcription factor Y subunit gamma
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4802
Human Swissprot No.
Q13952
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q13952/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18046
Mouse Swissprot No.
P70353
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P70353
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25337
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q62725
免疫原
The antiserum was produced against synthesized peptide derived from human NFYC. AA range:1-50
特异性
NF-YC Polyclonal Antibody detects endogenous levels of NF-YC protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
组织表达
Brain,Lymph node,Synovial membrane tissue,
信号通路
Antigen processing and presentation;
功能
function:Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.,similarity:Belongs to the NFYC/HAP5 subunit family.,subunit:Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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