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NFRκB Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3089
产品名称
NFRκB Rabbit Polyclonal Antibody
别名
NFRKB; INO80G; Nuclear factor related to kappa-B-binding protein; DNA-binding protein R kappa-B; INO80 complex subunit G
类别
常规抗体
基因名称
NFRKB
蛋白名称
Nuclear factor related to kappa-B-binding protein
推荐应用
WB
反应种属
Human,Mouse,Monkey
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
4798
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4798
Human Swissprot No.
Q6P4R8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6P4R8/entry
Mouse Gene ID
235134
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=235134
Mouse Swissprot No.
Q6PIJ4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6PIJ4
免疫原
The antiserum was produced against synthesized peptide derived from human NFRKB. AA range:463-512
特异性
NFRκB Polyclonal Antibody detects endogenous levels of NFRκB protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
预测分子量
110kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Component of the chromatin-remodeling INO80 complex, at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E.,tissue specificity:Expressed in thymus, brain, testes, spleen and liver.,
组织表达
Expressed in thymus, brain, testes, spleen and liver.
细胞定位
Nucleus .
功能
function:Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Component of the chromatin-remodeling INO80 complex, at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E.,tissue specificity:Expressed in thymus, brain, testes, spleen and liver.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from COS7 cells, using NFRKB Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using NFRκB Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

Western Blot analysis of COS7 cells using NFRκB Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

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