产品名称
NFRκB Rabbit Polyclonal Antibody
别名
NFRKB; INO80G; Nuclear factor related to kappa-B-binding protein; DNA-binding protein R kappa-B; INO80 complex subunit G
蛋白名称
Nuclear factor related to kappa-B-binding protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4798
Human Swissprot No.
Q6P4R8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6P4R8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=235134
Mouse Swissprot No.
Q6PIJ4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6PIJ4
免疫原
The antiserum was produced against synthesized peptide derived from human NFRKB. AA range:463-512
特异性
NFRκB Polyclonal Antibody detects endogenous levels of NFRκB protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Component of the chromatin-remodeling INO80 complex, at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E.,tissue specificity:Expressed in thymus, brain, testes, spleen and liver.,
组织表达
Expressed in thymus, brain, testes, spleen and liver.
功能
function:Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Component of the chromatin-remodeling INO80 complex, at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E.,tissue specificity:Expressed in thymus, brain, testes, spleen and liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.