产品名称
NF-1 Rabbit Polyclonal Antibody
别名
NFIA; KIAA1439; Nuclear factor 1 A-type; NF1-A; Nuclear factor 1/A; CCAAT-box-binding transcription factor; CTF; Nuclear factor I/A; NF-I/A; NFI-A; TGGCA-binding protein; NFIB; Nuclear factor 1 B-type; NF1-B; Nuclear factor 1/B; CCAAT-box-b
蛋白名称
Nuclear factor 1 A-type
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
4774/4781/4782/4784
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4774
Human Swissprot No.
Q12857/O00712/P08651/Q14938
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q12857/entry
Mouse Gene ID
18027/18028/18029/18032
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18027
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25492
Rat Swissprot Link
http://www.uniprot.org/uniprot/P09414
免疫原
The antiserum was produced against synthesized peptide derived from human Nuclear Factor 1. AA range:11-60
特异性
NF-1 Polyclonal Antibody detects endogenous levels of NF-1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
组织表达
Brain,Epithelium,Skeletal muscle,Testis,
功能
function:Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CTF/NF-I family.,similarity:Contains 1 CTF/NF-I DNA-binding domain.,subunit:Binds DNA as a homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
