产品名称
Neuromedin-U Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10874
Human Swissprot No.
P48645
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P48645/entry
Mouse Swissprot No.
Q9QXK8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9QXK8
免疫原
The antiserum was produced against synthesized peptide derived from human NMU. AA range:125-174
特异性
Neuromedin-U Polyclonal Antibody detects endogenous levels of Neuromedin-U protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015],
组织表达
Expressed throughout the enteric nervous system with highest levels being found in the jejunum.
功能
function:Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder.,similarity:Belongs to the NmU family.,tissue specificity:Expressed throughout the enteric nervous system with highest levels being found in the jejunum.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
