产品名称
Neuro D2 Rabbit Polyclonal Antibody
别名
NEUROD2; BHLHA1; NDRF; Neurogenic differentiation factor 2; NeuroD2; Class A basic helix-loop-helix protein 1; bHLHa1; NeuroD-related factor; NDRF
蛋白名称
Neurogenic differentiation factor 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4761
Human Swissprot No.
Q15784
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15784/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18013
Mouse Swissprot No.
Q62414
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q62414
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54276
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q63689
免疫原
The antiserum was produced against synthesized peptide derived from human NDF2. AA range:61-110
特异性
Neuro D2 Polyclonal Antibody detects endogenous levels of Neuro D2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates. [provided by RefSeq, Jul 2008],
功能
function:Appears to mediate neuronal differentiation.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.