产品名称
NET-5 Rabbit Polyclonal Antibody
别名
TSPAN9; NET5; Tetraspanin-9; Tspan-9; Tetraspan NET-5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10867
Human Swissprot No.
O75954
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O75954/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=109246
Mouse Swissprot No.
Q8BJU2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BJU2
免疫原
The antiserum was produced against synthesized peptide derived from human NET-5. AA range:72-121
特异性
NET-5 Polyclonal Antibody detects endogenous levels of NET-5 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009],
组织表达
Expressed in megakaryocytes and platelets (at protein level).
细胞定位
Membrane ; Multi-pass membrane protein . Colocalizes with GP6 in tetraspanin microdomains on the platelet surface. .
功能
PTM:Glycosylated.,similarity:Belongs to the tetraspanin (TM4SF) family.,subcellular location:Colocalizes with GP6 in tetraspanin microdomains on the platelet surface.,subunit:Found in a complex with GP6.,tissue specificity:Expressed in megakaryocytes and platelets (at protein level).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
