产品名称
NDUFS5 Rabbit Polyclonal Antibody
别名
NDUFS5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5; Complex I-15 kDa; CI-15 kDa; NADH-ubiquinone oxidoreductase 15 kDa subunit
蛋白名称
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4725
Human Swissprot No.
O43920
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O43920/entry
Mouse Swissprot No.
Q99LY9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99LY9
免疫原
The antiserum was produced against synthesized peptide derived from human NDUFS5. AA range:57-106
特异性
NDUFS5 Polyclonal Antibody detects endogenous levels of NDUFS5 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 1, 4 and 17. [provided by RefSeq, May 2010],
组织表达
Blood vessels- blood vessel,Kidney,Umbilical cord blood,
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein . Mitochondrion intermembrane space .
信号通路
Oxidative phosphorylation;Alzheimer's disease;Parkinson's disease;Huntington's disease;
功能
function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFS5 subunit family.,subunit:Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
