产品名称
NDUFA4 Rabbit Polyclonal Antibody
别名
NDUFA4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunit
蛋白名称
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4697
Human Swissprot No.
O00483
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O00483/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17992
Mouse Swissprot No.
Q62425
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q62425
免疫原
The antiserum was produced against synthesized peptide derived from human NDUFA4. AA range:32-81
特异性
NDUFA4 Polyclonal Antibody detects endogenous levels of NDUFA4 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein .
信号通路
Oxidative phosphorylation;Alzheimer's disease;Parkinson's disease;Huntington's disease;
功能
function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFA4 subunit family.,subunit:Mammalian complex I is composed of 45 different subunits.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
