产品名称
NCKX6 Rabbit Polyclonal Antibody
别名
SLC24A6; NCKX6; NCLX; Sodium/potassium/calcium exchanger 6; Na(+)/K(+)/Ca(2+)-exchange protein 6; Solute carrier family 24 member 6
蛋白名称
Sodium/potassium/calcium exchanger 6
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80024
Human Swissprot No.
Q6J4K2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6J4K2/entry
Mouse Swissprot No.
Q925Q3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q925Q3
免疫原
The antiserum was produced against synthesized peptide derived from human SLC24A6. AA range:494-543
特异性
NCKX6 Polyclonal Antibody detects endogenous levels of NCKX6 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
SLC24A6 belongs to a family of potassium-dependent sodium/calcium exchangers that maintain cellular calcium homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion (Cai and Lytton, 2004 [PubMed 14625281]).[supplied by OMIM, Mar 2008],
组织表达
Present in pancreatic beta-cells (at protein level).
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .
功能
function:Transports Ca(2+) in exchange for either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. In contrast to other members of the family its function is independent of K(+).,miscellaneous:Strongly inhibited by zinc.,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
