产品名称
NCKX3 Rabbit Polyclonal Antibody
别名
SLC24A3; NCKX3; Sodium/potassium/calcium exchanger 3; Na(+)/K(+)/Ca(2+)-exchange protein 3; Solute carrier family 24 member 3
蛋白名称
Sodium/potassium/calcium exchanger 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57419
Human Swissprot No.
Q9HC58
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9HC58/entry
Mouse Swissprot No.
Q99PD7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99PD7
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q9EPQ0
免疫原
The antiserum was produced against synthesized peptide derived from human SLC24A3. AA range:354-403
特异性
NCKX3 Polyclonal Antibody detects endogenous levels of NCKX3 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008],
组织表达
Abundant in the brain (PubMed:11294880). Expressed at low levels in the aorta, uterus and intestine (PubMed:11294880).
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,tissue specificity:Abundant in the brain. Expressed at low levels in the aorta, uterus and intestine.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
