产品名称
NACAD Rabbit Polyclonal Antibody
别名
NACAD; KIAA0363; NAC-alpha domain-containing protein 1
蛋白名称
NAC-alpha domain-containing protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23148
Human Swissprot No.
O15069
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O15069/entry
Mouse Swissprot No.
Q5SWP3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5SWP3
免疫原
The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425
特异性
NACAD Polyclonal Antibody detects endogenous levels of NACAD protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,
细胞定位
Cytoplasm . Nucleus .
功能
function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
