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Myosin XVI Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT2951
产品名称
Myosin XVI Rabbit Polyclonal Antibody
别名
MYO16; KIAA0865; MYO16B; NYAP3; Unconventional myosin-XVI; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3; Unconventional myosin-16
类别
常规抗体
基因名称
MYO16
蛋白名称
Unconventional myosin-XVI
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
23026
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23026
Human Swissprot No.
Q9Y6X6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y6X6/entry
Mouse Swissprot No.
Q5DU14
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5DU14
免疫原
Synthesized peptide derived from Myosin XVI . at AA range: 1050-1130
特异性
Myosin XVI Polyclonal Antibody detects endogenous levels of Myosin XVI protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
预测分子量
200kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development.,similarity:Contains 1 IQ domain.,similarity:Contains 2 myosin head-like domains.,similarity:Contains 7 ANK repeats.,subcellular location:Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells.,subunit:Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner.,
组织表达
Amygdala,Brain,
细胞定位
Cytoplasm . Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells. .
功能
function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development.,similarity:Contains 1 IQ domain.,similarity:Contains 2 myosin head-like domains.,similarity:Contains 7 ANK repeats.,subcellular location:Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells.,subunit:Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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