产品名称
Myosin XVI Rabbit Polyclonal Antibody
别名
MYO16; KIAA0865; MYO16B; NYAP3; Unconventional myosin-XVI; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3; Unconventional myosin-16
蛋白名称
Unconventional myosin-XVI
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23026
Human Swissprot No.
Q9Y6X6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y6X6/entry
Mouse Swissprot No.
Q5DU14
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5DU14
免疫原
Synthesized peptide derived from Myosin XVI . at AA range: 1050-1130
特异性
Myosin XVI Polyclonal Antibody detects endogenous levels of Myosin XVI protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development.,similarity:Contains 1 IQ domain.,similarity:Contains 2 myosin head-like domains.,similarity:Contains 7 ANK repeats.,subcellular location:Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells.,subunit:Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner.,
细胞定位
Cytoplasm . Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells. .
功能
function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development.,similarity:Contains 1 IQ domain.,similarity:Contains 2 myosin head-like domains.,similarity:Contains 7 ANK repeats.,subcellular location:Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells.,subunit:Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.