产品名称
MxB Rabbit Polyclonal Antibody
别名
MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein
蛋白名称
Interferon-induced GTP-binding protein Mx2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4600
Human Swissprot No.
P20592
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P20592/entry
Mouse Swissprot No.
Q9WVP9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WVP9
免疫原
Synthesized peptide derived from the Internal region of human MxB.
特异性
MxB Polyclonal Antibody detects endogenous levels of MxB protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Nucleus, nuclear pore complex . Localization to nuclear pores requires GTP-binding.
功能
induction:By interferons.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.