产品名称
MRP-S35 Rabbit Polyclonal Antibody
别名
MRPS35; MRPS28; HDCMD11P; MDS023; PSEC0213; 28S ribosomal protein S35; mitochondrial; MRP-S35; S35mt; 28S ribosomal protein S28, mitochondrial; MRP-S28; S28mt
蛋白名称
28S ribosomal protein S35 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60488
Human Swissprot No.
P82673
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P82673/entry
Mouse Swissprot No.
Q8BJZ4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BJZ4
免疫原
The antiserum was produced against synthesized peptide derived from human MRPS35. AA range:211-260
特异性
MRP-S35 Polyclonal Antibody detects endogenous levels of MRP-S35 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on
组织表达
Colon,Dendritic cell,Embryo,Hematopoietic stem cell,Lung,Melanoma,P
功能
subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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