产品名称
MRP-S21 Rabbit Polyclonal Antibody
别名
MRPS21; RPMS21; MDS016; 28S ribosomal protein S21; mitochondrial; MRP-S21; S21mt
蛋白名称
28S ribosomal protein S21 mitochondrial
反应种属
Human,Mouse,Rat,Monkey
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54460
Human Swissprot No.
P82921
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P82921/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66292
Mouse Swissprot No.
P58059
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P58059
免疫原
The antiserum was produced against synthesized peptide derived from human MRPS21. AA range:38-87
特异性
MRP-S21 Polyclonal Antibody detects endogenous levels of MRP-S21 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice varian
组织表达
Brain,Cerebellum,Hematopoietic stem cell,Lung,Testis,Uterus,
功能
similarity:Belongs to the ribosomal protein S21P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
