产品名称
MRP-S18C Rabbit Polyclonal Antibody
别名
MRPS18C; CGI-134; 28S ribosomal protein S18c; mitochondrial; MRP-S18-c; Mrps18-c; S18mt-c; 28S ribosomal protein S18-1, mitochondrial; MRP-S18-1
蛋白名称
28S ribosomal protein S18c mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51023
Human Swissprot No.
Q9Y3D5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y3D5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68735
Mouse Swissprot No.
Q8R2L5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R2L5
免疫原
The antiserum was produced against synthesized peptide derived from human MRPS18C. AA range:71-120
特异性
MRP-S18C Polyclonal Antibody detects endogenous levels of MRP-S18C protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondria
功能
similarity:Belongs to the ribosomal protein S18P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
