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MRP-S12 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT2874
产品名称
MRP-S12 Rabbit Polyclonal Antibody
别名
MRPS12; RPMS12; RPSM12; 28S ribosomal protein S12; mitochondrial; MRP-S12; S12mt; MT-RPS12
类别
常规抗体
基因名称
MRPS12
蛋白名称
28S ribosomal protein S12 mitochondrial
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
6183
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6183
Human Swissprot No.
O15235
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O15235/entry
Mouse Gene ID
24030
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24030
Mouse Swissprot No.
O35680
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35680
免疫原
The antiserum was produced against synthesized peptide derived from human MRPS12. AA range:21-70
特异性
MRP-S12 Polyclonal Antibody detects endogenous levels of MRP-S12 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
预测分子量
20kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. Th
组织表达
Brain,Colon,Liver,Skin,
细胞定位
Mitochondrion .
功能
similarity:Belongs to the ribosomal protein S12P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of MRPS12 Antibody. The lane on the right is blocked with the MRPS12 peptide.

Western blot analysis of the lysates from HepG2 cells using MRPS12 antibody.

Western Blot analysis of various cells using MRP-S12 Polyclonal Antibody diluted at 1:1000

Western Blot analysis of SH-SY5Y cells using MRP-S12 Polyclonal Antibody diluted at 1:1000

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