产品名称
MRP-L50 Rabbit Polyclonal Antibody
别名
MRPL50; 39S ribosomal protein L50; mitochondrial; L50mt; MRP-L50
蛋白名称
39S ribosomal protein L50 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54534
Human Swissprot No.
Q8N5N7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8N5N7/entry
Mouse Swissprot No.
Q8VDT9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VDT9
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL50. AA range:109-158
特异性
MRP-L50 Polyclonal Antibody detects endogenous levels of MRP-L50 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008],
组织表达
Carcinoma,Epithelium,Hepatoma,Skin,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
