产品名称
MRP-L49 Rabbit Polyclonal Antibody
别名
MRPL49; C11orf4; NOF1; OK/SW-cl.67; 39S ribosomal protein L49; mitochondrial; L49mt; MRP-L49; Neighbor of FAU; NOF; Protein NOF1
蛋白名称
39S ribosomal protein L49 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=740
Human Swissprot No.
Q13405
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q13405/entry
Mouse Swissprot No.
Q9CQ40
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CQ40
免疫原
Synthesized peptide derived from MRP-L49 . at AA range: 10-90
特异性
MRP-L49 Polyclonal Antibody detects endogenous levels of MRP-L49 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. [provided by RefSeq, May 2011],
功能
similarity:Belongs to the ribosomal protein L49em family.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.