产品名称
MRP-L47 Rabbit Polyclonal Antibody
别名
MRPL47; NCM1; CGI-204; 39S ribosomal protein L47; mitochondrial; L47mt; MRP-L47; Nasopharyngeal carcinoma metastasis-related protein 1
蛋白名称
39S ribosomal protein L47 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57129
Human Swissprot No.
Q9HD33
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9HD33/entry
Mouse Swissprot No.
Q8K2Y7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K2Y7
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL47. AA range:191-240
特异性
MRP-L47 Polyclonal Antibody detects endogenous levels of MRP-L47 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identifie
功能
sequence caution:Chimeric cDNA. Seems to include a portion of the orthologous murine sequence.,similarity:Belongs to the ribosomal protein L47em family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
