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MRP-L24 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT2855
产品名称
MRP-L24 Rabbit Polyclonal Antibody
别名
MRPL24; 39S ribosomal protein L24; mitochondrial; L24mt; MRP-L24
类别
常规抗体
基因名称
MRPL24
蛋白名称
39S ribosomal protein L24 mitochondrial
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
79590
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79590
Human Swissprot No.
Q96A35
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96A35/entry
Mouse Gene ID
67707
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67707
Mouse Swissprot No.
Q9CQ06
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CQ06
Rat Gene ID
295224
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=295224
Rat Swissprot No.
Q66H47
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q66H47
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL24. AA range:101-150
特异性
MRP-L24 Polyclonal Antibody detects endogenous levels of MRP-L24 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
预测分子量
32kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],
组织表达
Adipose tissue,Bone marrow,Ovary,
细胞定位
Mitochondrion .
功能
similarity:Belongs to the ribosomal protein L24P family.,similarity:Contains 1 KOW domain.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MRPL24 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from HUVEC cells, using MRPL24 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using MRP-L24 Polyclonal Antibody diluted at 1:2000

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