产品名称
MRP-L24 Rabbit Polyclonal Antibody
别名
MRPL24; 39S ribosomal protein L24; mitochondrial; L24mt; MRP-L24
蛋白名称
39S ribosomal protein L24 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79590
Human Swissprot No.
Q96A35
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96A35/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67707
Mouse Swissprot No.
Q9CQ06
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CQ06
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=295224
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q66H47
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL24. AA range:101-150
特异性
MRP-L24 Polyclonal Antibody detects endogenous levels of MRP-L24 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],
组织表达
Adipose tissue,Bone marrow,Ovary,
功能
similarity:Belongs to the ribosomal protein L24P family.,similarity:Contains 1 KOW domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.