产品名称
MRP-L22 Rabbit Polyclonal Antibody
别名
MRPL22; MRPL25; RPML25; HSPC158; 39S ribosomal protein L22; mitochondrial; L22mt; MRP-L22; 39S ribosomal protein L25, mitochondrial; L25mt; MRP-L25
蛋白名称
39S ribosomal protein L22 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29093
Human Swissprot No.
Q9NWU5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NWU5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=216767
Mouse Swissprot No.
Q8BU88
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BU88
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=287302
Rat Swissprot Link
http://www.uniprot.org/uniprot/P0C2C0
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL22. AA range:91-140
特异性
MRP-L22 Polyclonal Antibody detects endogenous levels of MRP-L22 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provide
组织表达
Carcinoma,Retina,Skin,Testis,Umbilical cord blood,
功能
similarity:Belongs to the ribosomal protein L22P family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
