产品名称
MRP-L21 Rabbit Polyclonal Antibody
别名
MRPL21; 39S ribosomal protein L21; mitochondrial; L21mt; MRP-L21
蛋白名称
39S ribosomal protein L21 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=219927
Human Swissprot No.
Q7Z2W9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q7Z2W9/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=353242
Mouse Swissprot No.
Q9D1N9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D1N9
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL21. AA range:131-180
特异性
MRP-L21 Polyclonal Antibody detects endogenous levels of MRP-L21 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008],
功能
similarity:Belongs to the ribosomal protein L21P family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
