产品名称
MRP-L20 Rabbit Polyclonal Antibody
别名
MRPL20; 39S ribosomal protein L20; mitochondrial; L20mt; MRP-L20
蛋白名称
39S ribosomal protein L20 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55052
Human Swissprot No.
Q9BYC9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BYC9/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66448
Mouse Swissprot No.
Q9CQL4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CQL4
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL20. AA range:100-149
特异性
MRP-L20 Polyclonal Antibody detects endogenous levels of MRP-L20 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
组织表达
Bone marrow,Lymph,Mammary gland,Whole embryo,
功能
similarity:Belongs to the ribosomal protein L20P family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.