产品名称
MRP-L15 Rabbit Polyclonal Antibody
别名
MRPL15; HSPC145; 39S ribosomal protein L15; mitochondrial; L15mt; MRP-L15
蛋白名称
39S ribosomal protein L15 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29088
Human Swissprot No.
Q9P015
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9P015/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27395
Mouse Swissprot No.
Q9CPR5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CPR5
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL15. AA range:191-240
特异性
MRP-L15 Polyclonal Antibody detects endogenous levels of MRP-L15 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008],
组织表达
Blood,Cervix,Fetal brain,
功能
similarity:Belongs to the ribosomal protein L15P family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
