产品名称
MOX-2 Rabbit Polyclonal Antibody
别名
MEOX2; GAX; MOX2; Homeobox protein MOX-2; Growth arrest-specific homeobox; Mesenchyme homeobox 2
蛋白名称
Homeobox protein MOX-2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4223
Human Swissprot No.
P50222
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P50222/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17286
Mouse Swissprot No.
P32443
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P32443
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29279
Rat Swissprot Link
http://www.uniprot.org/uniprot/P39020
免疫原
The antiserum was produced against synthesized peptide derived from human MEOX2. AA range:151-200
特异性
MOX-2 Polyclonal Antibody detects endogenous levels of MOX-2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus speckle .
功能
function:Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.,polymorphism:The poly-His region of MEOX2 is polymorphic and the number of His varies in the population.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with RNF10.,tissue specificity:Embryo and placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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