产品名称
Mos Rabbit Polyclonal Antibody
别名
MOS; Proto-oncogene serine/threonine-protein kinase mos; Oocyte maturation factor mos; Proto-oncogene c-Mos
蛋白名称
Proto-oncogene serine/threonine-protein kinase mos
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4342
Human Swissprot No.
P00540
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P00540/entry
Mouse Swissprot No.
P00536
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P00536
免疫原
The antiserum was produced against synthesized peptide derived from human MOS. AA range:61-110
特异性
Mos Polyclonal Antibody detects endogenous levels of Mos protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009],
组织表达
Expressed specifically in testis during spermatogenesis.
信号通路
Regulation of Actin Dynamics; MAPK_ERK_Growth;MAPK_G_Protein; Cell Growth
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed specifically in testis during spermatogenesis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.