产品名称
MMTAG2 Rabbit Polyclonal Antibody
别名
MMTAG2; C1orf35; Multiple myeloma tumor-associated protein 2; hMMTAG2
蛋白名称
Multiple myeloma tumor-associated protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79169
Human Swissprot No.
Q9BU76
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BU76/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67862
Mouse Swissprot No.
Q99LX5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99LX5
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=303180
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5M9I6
免疫原
The antiserum was produced against synthesized peptide derived from human MMTAG2. AA range:10-59
特异性
MMTAG2 Polyclonal Antibody detects endogenous levels of MMTAG2 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
组织表达
Blood,Caudate nucleus,Lymph,Myeloma,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
