产品名称
Megsin Rabbit Polyclonal Antibody
别名
SERPINB7; Serpin B7; Megsin; TP55
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8710
Human Swissprot No.
O75635
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O75635/entry
Mouse Swissprot No.
Q9D695
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D695
免疫原
The antiserum was produced against synthesized peptide derived from human SERPINB7. AA range:111-160
特异性
Megsin Polyclonal Antibody detects endogenous levels of Megsin protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],
组织表达
Predominantly expressed in mesangial cells. Expressed in the epidermis of the whole body.
功能
function:Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Predominantly expressed in mesangial cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
