产品名称
MDM1 Rabbit Polyclonal Antibody
别名
MDM1; Nuclear protein MDM1
蛋白名称
Nuclear protein MDM1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56890
Human Swissprot No.
Q8TC05
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8TC05/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17245
Mouse Swissprot No.
Q9D067
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D067
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=314859
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5PQN4
免疫原
The antiserum was produced against synthesized peptide derived from human MDM1. AA range:665-714
特异性
MDM1 Polyclonal Antibody detects endogenous levels of MDM1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],
组织表达
Brain,Epithelium,Prostate,Testis,Trachea,
细胞定位
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localizes to the centriole lumen. .
功能
similarity:Belongs to the MDM1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.