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MDM1 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT2689
产品名称
MDM1 Rabbit Polyclonal Antibody
别名
MDM1; Nuclear protein MDM1
类别
常规抗体
基因名称
MDM1
蛋白名称
Nuclear protein MDM1
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
56890
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56890
Human Swissprot No.
Q8TC05
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8TC05/entry
Mouse Gene ID
17245
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17245
Mouse Swissprot No.
Q9D067
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D067
Rat Gene ID
314859
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=314859
Rat Swissprot No.
Q5PQN4
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5PQN4
免疫原
The antiserum was produced against synthesized peptide derived from human MDM1. AA range:665-714
特异性
MDM1 Polyclonal Antibody detects endogenous levels of MDM1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
预测分子量
80kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],
组织表达
Brain,Epithelium,Prostate,Testis,Trachea,
细胞定位
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localizes to the centriole lumen. .
功能
similarity:Belongs to the MDM1 family.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of MDM1 Antibody. The lane on the right is blocked with the MDM1 peptide.

Western blot analysis of the lysates from HepG2 cells using MDM1 antibody.

Western Blot analysis of 3T3 cells using MDM1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

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