BD-PT2682

MCT12 Rabbit Polyclonal Antibody

SLC16A12; MCT12; Monocarboxylate transporter 12; MCT 12; Solute carrier family 16 member 12

常规抗体

SLC16A12

Monocarboxylate transporter 12

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

387700

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=387700

Q6ZSM3

http://www.uniprot.org/uniprotkb/Q6ZSM3/entry

240638

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=240638

Q8BGC3

http://www.uniprot.org/uniprot/Q8BGC3

The antiserum was produced against synthesized peptide derived from human MOT12. AA range:115-164

MCT12 Polyclonal Antibody detects endogenous levels of MCT12 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

53kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010],

Most highly expressed in kidney, followed by retina, lung, heart and testis. Very weakly expressed in brain and liver. Also detected in lens.

Cell membrane ; Multi-pass membrane protein .

disease:Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG) [MIM:612018]. Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies.,function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates.,similarity:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.,tissue specificity:Most highly expressed in kidney, followed by retina, lung, and testis. Very weakly expressed in brain and liver. Also detected in lens.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.