产品名称
MAST4 Rabbit Polyclonal Antibody
别名
MAST4; KIAA0303; Microtubule-associated serine/threonine-protein kinase 4
蛋白名称
Microtubule-associated serine/threonine-protein kinase 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=375449
Human Swissprot No.
O15021
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O15021/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=328329
Mouse Swissprot No.
Q811L6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q811L6
免疫原
The antiserum was produced against synthesized peptide derived from human MAST4. AA range:251-300
特异性
MAST4 Polyclonal Antibody detects endogenous levels of MAST4 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the microtubule-associated serine/threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
组织表达
Highly expressed in most normal human tissues, with an exception of in testis, small intestine, colon and peripheral blood leukocyte.
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,cofactor:Magnesium.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highly expressed in most normal human tissues, with an exception of in testis, small intestine, colon and peripheral blood leukocyte.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.