产品名称
Maspin Rabbit Polyclonal Antibody
别名
SERPINB5; PI5; Serpin B5; Maspin; Peptidase inhibitor 5; PI-5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5268
Human Swissprot No.
P36952
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P36952/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20724
Mouse Swissprot No.
P70124
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P70124
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116589
Rat Swissprot Link
http://www.uniprot.org/uniprot/P70564
免疫原
The antiserum was produced against synthesized peptide derived from human Serpin B5. AA range:91-140
特异性
Maspin Polyclonal Antibody detects endogenous levels of Maspin protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
组织表达
Normal mammary epithelial cells.
细胞定位
Secreted, extracellular space.
功能
function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
