产品名称
Mash2 Rabbit Polyclonal Antibody
别名
ASCL2; BHLHA45; HASH2; Achaete-scute homolog 2; ASH-2; hASH2; Class A basic helix-loop-helix protein 45; bHLHa45; Mash2
蛋白名称
Achaete-scute homolog 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=430
Human Swissprot No.
Q99929
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q99929/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17173
Mouse Swissprot No.
O35885
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35885
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24209
Rat Swissprot Link
http://www.uniprot.org/uniprot/P19360
免疫原
Synthesized peptide derived from Mash2 . at AA range: 1-80
特异性
Mash2 Polyclonal Antibody detects endogenous levels of Mash2 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
achaete-scute family bHLH transcription factor 2(ASCL2) Homo sapiens This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008],
组织表达
Expressed specifically in the extravillous trophoblasts of the developing placenta.
功能
function:AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Expressed specifically in the extravillous trophoblasts of the developing placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
