产品名称
MAP-9 Rabbit Polyclonal Antibody
别名
MAP9; ASAP; Microtubule-associated protein 9; Aster-associated protein
蛋白名称
Microtubule-associated protein 9
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79884
Human Swissprot No.
Q49MG5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q49MG5/entry
Mouse Swissprot No.
Q3TRR0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3TRR0
免疫原
The antiserum was produced against synthesized peptide derived from human MAP9. AA range:121-170
特异性
MAP-9 Polyclonal Antibody detects endogenous levels of MAP-9 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008],
组织表达
Amygdala,Bone marrow,Brain,
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.
功能
developmental stage:Constitutively expressed during the cell cycle.,function:Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.,subunit:Binds to purified microtubules via its C-terminus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
