产品名称
LYPLA1 Rabbit Polyclonal Antibody
别名
LYPLA1; APT1; LPL1; Acyl-protein thioesterase 1; APT-1; hAPT1; Lysophospholipase 1; Lysophospholipase I; LPL-I; LysoPLA I
蛋白名称
Acyl-protein thioesterase 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10434
Human Swissprot No.
O75608
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O75608/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18777
Mouse Swissprot No.
P97823
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P97823
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25514
Rat Swissprot Link
http://www.uniprot.org/uniprot/P70470
免疫原
The antiserum was produced against synthesized peptide derived from human LYPLA1. AA range:51-100
特异性
LYPLA1 Polyclonal Antibody detects endogenous levels of LYPLA1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013],
细胞定位
Cytoplasm . Cell membrane . Nucleus membrane . Endoplasmic reticulum . Shows predominantly a cytoplasmic localization with a weak expression in the cell membrane, nuclear membrane and endoplasmic reticulum. .
信号通路
Glycerophospholipid metabolism;
功能
catalytic activity:Palmitoyl-protein + H(2)O = palmitate + protein.,function:Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Also has low lysophospholipase activity.,similarity:Belongs to the AB hydrolase 2 family.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
