产品名称
LUC7L2 Rabbit Polyclonal Antibody
别名
LUC7L2; CGI-59; CGI-74; Putative RNA-binding protein Luc7-like 2
蛋白名称
Putative RNA-binding protein Luc7-like 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51631
Human Swissprot No.
Q9Y383
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y383/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=192196
Mouse Swissprot No.
Q7TNC4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TNC4
免疫原
The antiserum was produced against synthesized peptide derived from human LUC7L2. AA range:129-178
特异性
LUC7L2 Polyclonal Antibody detects endogenous levels of LUC7L2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
组织表达
Brain,Epithelium,Skin,Uterus,
细胞定位
Nucleus speckle . Nucleus, nucleoplasm . Colocalizes with SCNM1 and SNRNP70 in nuclear speckles. .
功能
function:May bind to RNA via its Arg/Ser-rich domain.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Luc7 family.,similarity:Contains 1 C2H2-type zinc finger.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
