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LTK Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT2598
产品名称
LTK Rabbit Polyclonal Antibody
别名
LTK; TYK1; Leukocyte tyrosine kinase receptor; Protein tyrosine kinase 1
类别
常规抗体
基因名称
LTK
蛋白名称
Leukocyte tyrosine kinase receptor
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
4058
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4058
Human Swissprot No.
P29376
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P29376/entry
Mouse Gene ID
17005
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17005
Mouse Swissprot No.
P08923
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P08923
免疫原
The antiserum was produced against synthesized peptide derived from human LTK. AA range:206-255
特异性
LTK Polyclonal Antibody detects endogenous levels of LTK protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
预测分子量
92kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
leukocyte receptor tyrosine kinase(LTK) Homo sapiens The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
组织表达
Expressed in non-hematopoietic cell lines and T- and B-cell lines.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
alternative products:Additional isoforms seem to exist,catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:The exact function of this protein is not known. It is probably a receptor with a tyrosine-protein kinase activity.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in non-hematopoietic cell lines and T- and B-cell lines.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from Jurkat cells, using LTK Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HeLa cells using LTK antibody.

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