产品名称
LTK Rabbit Polyclonal Antibody
别名
LTK; TYK1; Leukocyte tyrosine kinase receptor; Protein tyrosine kinase 1
蛋白名称
Leukocyte tyrosine kinase receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4058
Human Swissprot No.
P29376
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P29376/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17005
Mouse Swissprot No.
P08923
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P08923
免疫原
The antiserum was produced against synthesized peptide derived from human LTK. AA range:206-255
特异性
LTK Polyclonal Antibody detects endogenous levels of LTK protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
leukocyte receptor tyrosine kinase(LTK) Homo sapiens The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
组织表达
Expressed in non-hematopoietic cell lines and T- and B-cell lines.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
alternative products:Additional isoforms seem to exist,catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:The exact function of this protein is not known. It is probably a receptor with a tyrosine-protein kinase activity.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in non-hematopoietic cell lines and T- and B-cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.