产品名称
LSP1 Rabbit Polyclonal Antibody
别名
LSP1; WP34; Lymphocyte-specific protein 1; 47 kDa actin-binding protein; 52 kDa phosphoprotein; pp52; Lymphocyte-specific antigen WP34
蛋白名称
Lymphocyte-specific protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4046
Human Swissprot No.
P33241
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P33241/entry
Mouse Swissprot No.
P19973
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P19973
免疫原
The antiserum was produced against synthesized peptide derived from human LSP1. AA range:104-153
特异性
LSP1 Polyclonal Antibody detects endogenous levels of LSP1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
组织表达
Activated T-lymphocytes.
细胞定位
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
功能
function:May play a role in mediating neutrophil activation and chemotaxis.,PTM:Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis.,subunit:Binds actin.,tissue specificity:Activated T-lymphocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
