产品名称
LPAAT-ε Rabbit Polyclonal Antibody
别名
AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon; 1-acylglycerol-3-phosphate O-acyltransferase 5; 1-AGP acyltransferase 5; 1-AGPAT 5; Lysophosphatidic acid acyltransferase epsilon; LPAAT-epsilon
蛋白名称
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55326
Human Swissprot No.
Q9NUQ2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NUQ2/entry
Mouse Swissprot No.
Q9D1E8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D1E8
免疫原
The antiserum was produced against synthesized peptide derived from human AGPAT5. AA range:241-290
特异性
LPAAT-ε Polyclonal Antibody detects endogenous levels of LPAAT-ε protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. A pseudogene of this gene is present on the Y chromosome. [provided by RefSeq, Aug 2014],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Nucleus envelope . Mitochondrion .
功能
catalytic activity:Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.,caution:It is uncertain whether Met-1 or Met-12 is the initiator.,domain:The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.,function:Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.,pathway:Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
