产品名称
LPAAT-δ Rabbit Polyclonal Antibody
别名
AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 4; 1-AGP acyltransferase 4; 1-AGPAT 4; Lysophosphatidic acid acyltransferase delta; LPAAT-delta
蛋白名称
1-acyl-sn-glycerol-3-phosphate acyltransferase delta
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56895
Human Swissprot No.
Q9NRZ5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NRZ5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68262
Mouse Swissprot No.
Q8K4X7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K4X7
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170919
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q924S1
免疫原
The antiserum was produced against synthesized peptide derived from human AGPAT4. AA range:151-200
特异性
LPAAT-δ Polyclonal Antibody detects endogenous levels of LPAAT-δ protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008],
组织表达
Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
信号通路
Glycerolipid metabolism;Glycerophospholipid metabolism;Ether lipid metabolism;
功能
catalytic activity:Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.,domain:The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.,function:Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.,pathway:Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
