产品名称
LGR6 Rabbit Polyclonal Antibody
别名
LGR6; Leucine-rich repeat-containing G-protein coupled receptor 6
蛋白名称
Leucine-rich repeat-containing G-protein coupled receptor 6
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59352
Human Swissprot No.
Q9HBX8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9HBX8/entry
Mouse Swissprot No.
Q3UVD5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UVD5
免疫原
The antiserum was produced against synthesized peptide derived from human LGR6. AA range:471-520
特异性
LGR6 Polyclonal Antibody detects endogenous levels of LGR6 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Orphan receptor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 16 LRR (leucine-rich) repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
