产品名称
LASS4 Rabbit Polyclonal Antibody
别名
CERS4; LASS4; Ceramide synthase 4; CerS4; LAG1 longevity assurance homolog 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79603
Human Swissprot No.
Q9HA82
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9HA82/entry
Mouse Swissprot No.
Q9D6J1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D6J1
免疫原
The antiserum was produced against synthesized peptide derived from human LASS4. AA range:41-90
特异性
LASS4 Polyclonal Antibody detects endogenous levels of LASS4 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,
组织表达
Cerebellum,Embryo,Lung,
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
