产品名称
KKIAMRE Rabbit Polyclonal Antibody
别名
CDKL2; Cyclin-dependent kinase-like 2; Protein kinase p56 KKIAMRE; Serine/threonine-protein kinase KKIAMRE
蛋白名称
Cyclin-dependent kinase-like 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8999
Human Swissprot No.
Q92772
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q92772/entry
Mouse Swissprot No.
Q9QUK0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9QUK0
免疫原
The antiserum was produced against synthesized peptide derived from human CDKL2. AA range:211-260
特异性
KKIAMRE Polyclonal Antibody detects endogenous levels of KKIAMRE protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008],
组织表达
Expressed in testis and kidney, and at lower level in brain and lung.
细胞定位
Cytoplasm . Nucleus .
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis and kidney, and at lower level in brain and lung.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
